Efficacy of Antibiotic Therapy and Appendectomy Quantitative Research

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Updated: Dec 15th, 2023

Validity

It is necessary to note that choosing the most appropriate research method can be a challenging task but the validity of the research depends on this choice and, hence, evaluation of a research plays an important role (Picardi and Masick 10). The article in question dwells upon the efficacy of antibiotic therapy and appendectomy in patients with uncomplicated acute appendicitis (Salminen et al. 2340).

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To evaluate the article, it is possible to consider its face validity that will show the way people see the test (McQueen and Knussen 144). It is possible to assume that the research seems valid due to its attention to two types of treatment. It involves quite a significant number of patients who were chosen randomly. There seems to be no bias or inconsistency (McBurney and White 185).

At the same time, the article’s validity is quite doubtful as the correlations were not totally free of confounds. The research in question is characterized by certain degree of bias as the third variable interferes with its results (Nestor and Schutt 49). Thus, the health issue is similar to all the patients but health conditions are all different.

However, the age of participants ranges from 18 to 60 and it is clear that these age groups are characterized by certain health conditions that could have a considerable effect on the efficiency of antibiotics. Lifestyles of patients (their diets, bad habits and so on) were not taken into account and this aspect could have a significant impact on efficacy of treatment as well.

Importantly, patients’ lifestyle after the treatment was not considered and it could affect the results of the research. Therefore, it is possible to note that the validity of the research could be doubtful even though it seems to address the research question and it is based on the right research method.

Statistical Methods

The researchers used categorical variables characterized by percentages and frequencies. They applied the Pearson χ2 test. This statistical method is quite relevant as it is aimed at revealing the likelihood of the difference between certain things, events and so on. The researchers hypothesize that the difference between efficacy of the two types of treatment will be 24% and the test helps them check their hypothesis.

Furthermore, the researchers also tried to eliminate any inaccuracy through addressing the variables. The researchers utilized the Mann-Whitney test. The Mann-Whitney test is employed when a non-parametric test is necessary. It enables researchers to test the median of groups of participants.

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As far as the research in question is concerned, the participants were characterized by different features (including different leukocyte count, creatinine and hemoglobin level, their age, gender and so on). Hence, the test helped the researchers to trace the median of the two groups of participants.

Finally, it is necessary to add that modern researchers may utilize various types of statistical software that helps them avoid any bias or inaccuracy (Stangor 343). It also saves a lot of time. The researchers also employed technology as they used SAS version 9.2.

Hence, it is possible to state that the research is based on solid statistical analysis of major data. The researchers use the statistical analysis that are consistent with their research questions and the purpose of the research. It is possible to state that the research is quite valid as it is based on efficient statistical tests.

Works Cited

McBurney, Donald, & and Theresa White. Research Methods. Belmont: Cengage Learning, 2009. Print.

McQueen, Ronald A., and Knussen, Christina. Introduction to Research Methods and Statistics in Psychology. Essex: Pearson, 2006. Print.

Nestor, Paul. G., and Russell K. Schutt. Research Methods in Psychology: Investigating Human Behavior. Thousand Oaks: SAGE Publications, 2014. Print.

Picardi, Carrie A., and Kevin D. Masick. Research Methods: Designing and Conducting Research with a Real-World Focus. Thousand Oaks: SAGE Publications, 2013. Print.

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Salminen, Paulina, Hannu Paajanen, Tero Rautio, Pia Nordström, Markku Aarnio, Tuomo Rantanen, Risto Tuominen, Saija Hurme, Johanna Virtanen, Jukka-Pekka Mecklin, Juhani Sand, Airi Jartti, Irina Rinta-Kiikka, and Juha M. Grönroos. “Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis: The APPAC Randomized Clinical Trial.” JAMA 313.23 (2015): 2340-2348. Print.

Stangor, Charles. Research Methods for the Behavioral Sciences. Belmont: Cengage Learning, 2014. Print.

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IvyPanda. (2023, December 15). Efficacy of Antibiotic Therapy and Appendectomy. https://ivypanda.com/essays/efficacy-of-antibiotic-therapy-and-appendectomy/

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"Efficacy of Antibiotic Therapy and Appendectomy." IvyPanda, 15 Dec. 2023, ivypanda.com/essays/efficacy-of-antibiotic-therapy-and-appendectomy/.

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IvyPanda. (2023) 'Efficacy of Antibiotic Therapy and Appendectomy'. 15 December.

References

IvyPanda. 2023. "Efficacy of Antibiotic Therapy and Appendectomy." December 15, 2023. https://ivypanda.com/essays/efficacy-of-antibiotic-therapy-and-appendectomy/.

1. IvyPanda. "Efficacy of Antibiotic Therapy and Appendectomy." December 15, 2023. https://ivypanda.com/essays/efficacy-of-antibiotic-therapy-and-appendectomy/.


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IvyPanda. "Efficacy of Antibiotic Therapy and Appendectomy." December 15, 2023. https://ivypanda.com/essays/efficacy-of-antibiotic-therapy-and-appendectomy/.

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