Ulcerative colitis or regional enteritis manifests through inflammation that can be either acute or chronic. The inflammation penetrates thus preceding across the layers, estimated from the bowel wall to intestinal mucosa. On the other hand, ulcerative colitis manifests by affecting the mucous membrane of the colon. Crohn’s disease is characterized by disappearance, reduction, or exacerbation of inflammation of the colon. Colitis is recognized by having many ulcerations, the colon epithelium’s ability to shed (Feuerstein & Cheifetz, 2017). As a result of edema, the condition exacerbates, leading to the tissues of the colon getting inflamed.
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In regional enteritis, the disease process commences from the formation of edema to the thickening of the intestinal mucosa’s inner lining. As the condition exacerbates, ulcers begin to develop on the inflamed tissues of the bowel wall. The lesions formed are not aligned systematically but are separated by the normal tissues that have not been affected. Invasion of lesions results in the formation of fistulas, crack, or fissures and destruction of tissues caused by a cavity covering the entire peritoneum. Thickening of the bowels occurs as the condition progresses further, as the lumen becomes narrow. As compared to ulcerative colitis, as the disease progresses, the lesions developed continuously and followed one another (Barnes et al., 2019). Abscesses formed affect the mucosa and submucosa of the colon. The worsening of the condition begins at the rectum and covers proximally, thus affecting the entire colon. Finally, hypertrophy and deposits of fats unfold due to narrowing, thickening, and shortening the bowel.
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Feuerstein, J. D., & Cheifetz, A. S. (2017). Crohn disease: Epidemiology, diagnosis, and management. In Mayo Clinic Proceedings (vol. 92, no. 7, pp. 1088-1103). Elsevier. Web.