In their article “Effects of Non-Surgical Periodontal Treatment on Clinical Response, Serum Inflammatory Parameters, and Metabolic Control in Patients with Type 2 Diabetes: A Randomized Study”, Lei Chen, Gang Luo, Dongying Xuan, Bihong Wei, Fang Liu, Jing Li, and Jincal Zhang aim to evaluate the effects of periodontal treatment on clinical response, systematic inflammatory parameters, and metabolic control in the group of patients with Type 2 diabetes. As a result of the research study, conducted within the frames of the studying process, the authors came to a conclusion that non-surgical periodontal treatment can effectively minimize periodontal and circulating status. To proceed with their findings, the researchers conducted their observations in two groups of patients. The total amount of patients, taking part in the investigation process, was 134. The evaluation of the results of the research justified the suppositions and conclusions made by the authors of the article. Overall, after addressing the article “Effects of Non-Surgical Periodontal Treatment on Clinical Response, Serum Inflammatory Parameters, and Metabolic Control in Patients with Type 2 Diabetes: A Randomized Study”, it can be said that its author’s utilized evidence-based research for making their conclusions, which proves that the results of the article’s study can be considered trustworthy and reliable.
First, speaking about whether the basis of the research in the article under consideration can be seen as a scientific and reliable one, as a result, it is important to address the method used by the authors. The information from the article states that its authors conducted research in two groups of patients with Type 2 Diabetes. The total amount of patients, participating in the research was 134. People were placed into the two groups on the basis of occasional selection. In both groups, patients were subjected to non-surgical treatment and regularly examined. The patient examination included not only clinical periodontal examination, but also patients’ blood was tested on the presence of hsCRP, TNF- an HbA1c, and FPG. Therefore, the research study of a patient’s condition in case of non-surgical treatment, conducted by the authors of the article, can be considered well-grounded scientifically.
Next, the other reason to evaluate the findings of the authors of the article under consideration as scientific and reliable is their approach to statistic calculations. To begin with, the researchers identified the proper timing of patient examination. Patients in both study groups were regularly examined: the initial examination took place at 1.5 month period; the second one was at 3 month period, and the third one was in a half a year period. All the results of patient examination along with the results of blood tests were carefully analyzed on the basis of statistical investigation. In particular, the authors took into consideration the fact that a standard deviation of 1.0% and enrolment of around 53 patients in a group may occur, while making their calculations. In addition, they utilized a one-way analysis of variance to assess continuous variables among the groups of participators in the experiment. From the point of view of statistical science, this enabled them to acquire reliable and trustworthy data as a result of their research study. Besides, the candidates for the investigated groups were selected on a random basis, which also suggests that the statistical veracity of the experiment is considerable.
Further, the statement, that the findings of the article under consideration can be seen as scientific, is advocated by the fact that the hypothesis of the authors was well-elaborated initially. Particularly, the authors based their hypothesis on the idea that chronic periodontitis has similar risk factors with Type 2 Diabetes including psychological stress, smoking, age, and neutrophil functional alterations. This concept has been argued about for a long time period, but today, it is proved in the research studies of numerous dentists and endocrinologists. The other model that supports the relevance of the initial hypothesis of the authors of the given article is in understanding that chronic periodontitis and Type 2 Diabetes cause the systematic immune response and a certain measure of immune-regulatory dysfunction. Therefore, a significant measure of similarity between the two pathologies and their symptoms identifies a connection between them, which is reflected in the initial hypothesis of the authors of the article.
As a final point, it is necessary to state that the findings of the article “Effects of Non-Surgical Periodontal Treatment on Clinical Response, Serum Inflammatory Parameters, and Metabolic Control in Patients with Type 2 Diabetes: A Randomized Study” can be seen as scientifically supported and reliable. This conclusion can be supported by a variety of facts. First, the method utilized by the authors of the article in their research study is well-elaborated scientifically. Next, during analyzing the results of investigations, held in study groups, modern and well-designed statistical approaches were implemented. Finally, even at the initial stage of their research study, the authors of the article made a great contribution to the scientific validity of their work by means of careful elaborating of their research hypothesis. Thus, the results of the research study, described in the article, can be seen as trustworthy and supported scientifically.