Obsessive-Compulsive Disorder Treatments Analysis Thesis

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Updated: Apr 9th, 2024

The Statistical Test Used

The study aims to use a multivariate analysis of variance (MANOVA) in comparing the effects of cognitive behavior therapy (CBT), behavior therapy (BT), and no treatment (NT) on actions and thoughts related to obsessive-compulsive disorder (OCD). MANOVA is an appropriate statistical test because the data have one independent variable with three categories and two dependent variables on a continuous scale. According to Denis (2016), MANOVA applies in the analysis of data to determine the effect of two or more independent groups on two or more continuous variables. Jackson (2015) holds that the nature of data in independent and dependent variables determines the type of statistical analysis. The independent variable is the treatment method comprising CBT, BT, and NT while the dependent variables are the occurrences of actions (obsession-related behaviors) and the occurrences of thoughts (obsession-related cognitions).

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The Basis of the Problem

The basis of the problem is that different methods of psychotherapy have different impacts on the treatment of OCD. As CBT and BT are two common methods employed in the treatment of OCD, NT was added as a control treatment method for comparison purposes to reveal the effect of both CBT and BT. Patients with OCD (N = 30) were sampled, and equal numbers (n = 10) were randomly assigned to CBT, BT, and NT groups. After treatment, the outcomes of these therapies were assessed by measuring the occurrences of actions (obsession-related behaviors) and the occurrences of thoughts (obsession-related cognitions). In this view, a comparative analysis of the outcomes of different therapies using MANOVA is essential to determine the most effective therapy.

Research Questions

  • What are the effects of CBT, BT, and NT on the occurrences of thoughts and actions among patients with obsessive-compulsive disorder?
  • Which is the best therapy in the treatment of obsessive-compulsive disorder among patients?

Hypothesis

The effects of CBT, BT, and NT on the occurrences of thoughts and actions among patients with obsessive-compulsive disorder are not statistically significant.

In answering the questions mentioned above and testing the hypothesis, the study utilized MANOVA. Warner (2012) explains that MANOVA uses the generalized linear model in establishing the relationships between dependent and independent variables. Descriptive statistics form the basis of MANOVA for they summarize data by highlighting inherent patterns and trends (Karter, 2016). The descriptive statistics show that there are apparent differences in the occurrences of actions and thoughts among patients with OCD in CBT, BT, and NT groups. Essentially, the descriptive statistics reveal that the occurrences of actions among CBT, BT, and NT groups (M = 4.53, SD = 1.456) are lower than the occurrences of thoughts among CBT, BT, and NT groups (M = 14.53, SD = 2.209).

Table 1.

Descriptive Statistics
groupMeanStd. DeviationN
Number of obsession-related behaviorsCBT4.901.19710
BT3.701.76710
No Treatment Control5.001.05410
Total4.531.45630
Number of obsession-related thoughtsCBT13.401.89710
BT15.202.09810
No Treatment Control15.002.35710
Total14.532.20930

Table 2.

Multivariate Tests
EffectValueFHypothesis dfError dfSig.
InterceptPillai’s Trace.983745.230b2.00026.000.000
Wilks’ Lambda.017745.230b2.00026.000.000
Hotelling’s Trace57.325745.230b2.00026.000.000
Roy’s Largest Root57.325745.230b2.00026.000.000
GroupPillai’s Trace.3182.5574.00054.000.049
Wilks’ Lambda.6992.555b4.00052.000.050
Hotelling’s Trace.4072.5464.00050.000.051
Roy’s Largest Root.3354.520c2.00027.000.020
a. Design: Intercept + Group
b. Exact statistic
c. The statistic is an upper bound on F that yields a lower bound on the significance level.

Multivariate analyses indicate that the effects of therapies on actions and thoughts of patients with OCD are statistically significant. According to Pillai’s trace, the effects of CBT, BT, and NT on the occurrences of obsessive actions and thoughts are statistically significant, V = 0.318, F(4,54) = 2.557, p = 0.049. Likewise, Wilkis’ Lambda indicates that CBT, BT, and NT have statistically significant effects on the occurrences of obsessive actions and thoughts, L = 0.699, F(4,54) = 2.555, p = 0.050. However, Hotelling’s trace reveals that CBT, BT, and NT do not have a statistically significant effect on the occurrences of obsessive actions and thoughts among patients with OCD, T = 0.407, F(4, 54) = 2.546, p = 0.051. Similar to Pillai’s trace and Wilkis’ Lambda, Roy’s largest root confirms that CBT, BT, and NT have a statistically significant effect on the occurrences of obsessive actions and thoughts among patients with OCD, Θ = 0.335, F(4,54) = 4.520, p = 0.020.

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Nevertheless, univariate analysis reveals that CBT, BT, and NT have no statistically significant effects on the occurrences of obsessive actions (F(2,27) = 2.77, p = 0.080) and the occurrences of obsessive thoughts (F(2,27) = 2.154, p = 0.136)

Table 3.

Tests of Between-Subjects Effects
SourceDependent VariableType III Sum of SquaresdfMean SquareFSig.
Corrected ModelNumber of obsession-related behaviors10.467a25.2332.771.080
Number of obsession-related thoughts19.467b29.7332.154.136
InterceptNumber of obsession-related behaviors616.5331616.533326.400.000
Number of obsession-related thoughts6336.53316336.5331402.348.000
GroupNumber of obsession-related behaviors10.46725.2332.771.080
Number of obsession-related thoughts19.46729.7332.154.136
ErrorNumber of obsession-related behaviors51.000271.889
Number of obsession-related thoughts122.000274.519
TotalNumber of obsession-related behaviors678.00030
Number of obsession-related thoughts6478.00030
Corrected TotalNumber of obsession-related behaviors61.46729
Number of obsession-related thoughts141.46729
a. R Squared =.170 (Adjusted R Squared =.109)
b. R Squared =.138 (Adjusted R Squared =.074)

Post hoc analysis (Table 4) shows that there are no statistically significant differences in the occurrences of obsessive actions and the occurrences of obsessive thoughts between treatment groups (p> 0.05).

Table 4.

Multiple Comparisons
Dependent Variable(I) group(J) groupMean Difference (I-J)Std. ErrorSig.95% Confidence Interval
Lower BoundUpper Bound
Number of obsession-related behaviorsGames-HowellCBTBT1.20.675.209-.542.94
No Treatment Control-.10.504.979-1.391.19
BTCBT-1.20.675.209-2.94.54
No Treatment Control-1.30.651.148-2.99.39
No Treatment ControlCBT.10.504.979-1.191.39
BT1.30.651.148-.392.99
Number of obsession-related thoughtsGames-HowellCBTBT-1.80.894.138-4.08.48
No Treatment Control-1.60.957.244-4.05.85
BTCBT1.80.894.138-.484.08
No Treatment Control.20.998.978-2.352.75
No Treatment ControlCBT1.60.957.244-.854.05
BT-.20.998.978-2.752.35
Based on observed means.
The error term is Mean Square (Error) = 4.519.

According to Pallant (2016) mean plot enhances exploratory analysis of data for it depicts the variation in means among different groups. The comparison of obsessive actions among treatment groups shows that BT has the lowest mean (Figure 1) while the comparison of obsessive thoughts reveals that CBT has the lowest mean (Figure 2).

Mean plot of obsessive actions.
Figure 1: Mean plot of obsessive actions.
Mean plot of obsessive thoughts.
Figure 2: Mean plot of obsessive thoughts.

Discriminant Analysis

The analysis of covariance matrices depicts that obsessive thoughts and actions have no significant relationship in the CBT group. Field (2013) asserts that discriminant analysis is necessary for it provides details about relationships established in MANOVA analysis. Furthermore, covariance matrices show that obsessive thoughts and actions have a positive relationship in the BT group. In contrast, covariance matrices reveal that obsessive thoughts and actions have a negative relationship in the NT group.

Table 5.

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Covariance Matrices
groupNumber of obsession-related behaviorsNumber of obsession-related thoughts
CBTNumber of obsession-related behaviors1.433.044
Number of obsession-related thoughts.0443.600
BTNumber of obsession-related behaviors3.1222.511
Number of obsession-related thoughts2.5114.400
No Treatment ControlNumber of obsession-related behaviors1.111-1.111
Number of obsession-related thoughts-1.1115.556

The discriminant analysis elucidates how two discriminant functions explain the discriminating ability of functions. Table 6 indicates that the first discriminating function accounts for 82.2% of the variance (R2 = 0.251) whereas the second discriminating function accounts for 17.8% of the variance (R2 = 0.068).

Table 6.

Eigenvalues
FunctionEigenvalue% of VarianceCumulative %Canonical Correlation
1.335a82.282.2.501
2.073a17.8100.0.260
a. The first 2 canonical discriminant functions were used in the analysis.

The combination of the two discriminating functions gives a significant differentiation of the treatment groups, L = 0.699, (4) = 9.508, p = 0.05. However, the removal of the first discriminating function shows that the second discriminating function does not have a statistically significant differentiation, L = 0.932, (4) =1.856, p = 0.173.

Table 7.

Wilks’ Lambda
Test of Function(s)Wilks’ LambdaChi-squaredfSig.
1 through 2.6999.5084.050
2.9321.8561.173

The structure matrix reveals the correlation between discriminating functions and how treatment outcomes load differently onto both functions. Evidently, obsessive actions load highly onto both the first discriminating function (r = 0.711) and the second discriminating function (r = 0.703). In contrast, obsessive thoughts load very highly onto the second discriminating function (r = 0.817) than the first discriminating function (r = -0.576).

Table 8.

Structure Matrix
Function
12
Number of obsession-related behaviors.711*.703
Number of obsession-related thoughts-.576.817*
A combined discriminant function plot.
Figure 3: A combined discriminant function plot.

he assessment of the discriminant function plot indicates that the first discriminating function differentiates the CBT group from the BT group. Comparatively, the second discriminating function differentiates the NT group from both BT and CBT groups.

Interpretation

Although descriptive statistics indicate that there are apparent differences in the means of obsessive actions and thoughts, the univariate analysis reveals that the differences are not statistically significant between the treatment groups. Coefficients of MANOVA, namely, Pillai’s trace, Wilks’ Lambda, and Roy’s largest root indicate that CBT, BT, and NT have a statistically significant effect on the occurrences of obsessive actions and thoughts. Post hoc analysis further reveals that there are no statistically significant differences in the occurrence of obsessive actions and thoughts based on treatment groups. Further analysis using the discriminant method suggests that differentiation of discriminating functions reveals underlying dimensions. Although the treatment methods appear to influence the occurrences of obsessive actions and thoughts, their distributions are inherent to OCD. In answering the first question, the data analysis established that the effects of CBT, BT, and NT have statistically significant effects on the occurrences of thoughts and actions among patients with OCD. CBT is the best treatment for obsessive thoughts whereas BT is the best treatment for obsessive actions among patients.

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References

Denis, D. (2016). Applied univariate, bivariate, and multivariate statistics. Hoboken, NJ: Wiley.

Field, A. (2013). Discovering statistics using IBM SPSS statistics (4th ed.). Los Angeles, CA: SAGE Publications.

Jackson, S. J. (2015). Research methods and statistics: A critical thinking approach (5th ed.). Belmont, CA: Cengage Learning.

Karter, J. (2016). Descriptive statistics and exploratory analysis of data with matlab. New York, NY: CreateSpace.

Pallant, J. (2016). SPSS survival manual: A step by step guide to data analysis using IBM SPSS. Sydney, Australia: Allen & Unwin.

Warner, R. M. (2012). Applied statistics: From bivariate through multivariate techniques: From bivariate through multivariate techniques (2nd ed.). New Delhi, India: Sage Publishers.

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