SIADH is an abbreviation that means syndrome of inappropriate antidiuretic hormone. A variety of sources can cause it, including medication, brain disorders, and lung disease. Antidiuretic hormone is responsible for filtering water and releasing it into circulation in a form that is free of various solutes. Insufficient or excessive production of the agent leads to a disruption of the chemical balance of the human body, which may create further issues. As such, SIADH is usually classified as a condition that requires treatment and treated with medications and solute infusions.
SIADH is characterized by increases in the amounts of ADH and a corresponding rise in kidneys’ efforts to filter water. As such, the body of the person affected by the syndrome will expel higher amounts of solutes than usual. Yarbro, Wujcik, and Gobel (2018) identify hyponatremia, disproportionately high urine osmolality, and an increased concentration of sodium in urine as the results. Fleisher and Rosenbaum (2018) identify conivaptan, demeclocycline hydrochloride, fludrocortisone, and hydrocortisone as efficient agents for treatment. The overall goal of the program will be to increase the patient’s solute levels by infusion and to eliminate the cause of the imbalance.
As long as proper care is administered in a timely reason, the danger SIADH poses to the patient’s health is not significant. The specialists will first identify the cause behind the syndrome and eliminate it if possible. In cases such as anesthetic-induced disruptions in the production of the hormone, the syndrome may pass without intervention. After the reasons for the condition’s emergence and the presence of hyponatremia or other symptoms are confirmed, the patient will receive appropriate treatment. In most cases, slow solute infusions, along with medication to eliminate the cause, should be sufficient.
References
Fleisher, L. A., & Rosenbaum, S. H. (Eds.). (2018). Complications in anesthesia (3rd ed.). Philadelphia, PA: Elsevier.
Yarbro, C. H., Wujcik, D., & Gobel, B. H. (Eds.). (2018). Cancer nursing: Principles and practice (8th ed.). Burlington, MA: Jones & Bartlett.