Calcium and Phosphorus Metabolism Essay

Exclusively available on Available only on IvyPanda® Made by Human No AI

Hypophosphatemia is a metabolic derangement characterized by an abnormally low phosphate level in the blood serum. Rickets in children occurs due to low phosphate serum levels, while Osteomalacia is due to phosphorus deficit in adults 1. Osteoporosis may be brought on by an imbalance in the body’s phosphorus and calcium levels in bone metabolism. If the body does not have enough calcium in the blood, metabolic derangement called hypocalcemia develops. Over time, cataracts, dental changes, and other abnormalities may develop due to hypocalcemia. Nails become brittle, hair grows slowly, and the skin becomes delicate and thin due to a lack of calcium. Muscle cramping, mental disorientation, and numb lips and hands are hypocalcemia’s severe symptoms. Calcium and phosphate ions release promote bone repair by controlling osteoblast and osteoclast activation. The calcium in the serum is affected by the phosphate level. There is an inverse relationship between calcium and phosphate in the body, meaning that phosphate levels decrease as calcium levels in the serum increase. PTH regulates calcium and phosphorus concentrations in the serum. Therefore, calcium and phosphorus interact to affect bone metabolism in the body.

Low blood calcium causes the release of PTH from the parathyroid gland (step 1).

PTH leads to the release of calcium from bones (step 2), leading to an increase in the serum calcium level (step 6a).

PTH affects the kidney by increasing the kidney’s conversion of 25-dihydroxy cholecalciferol to calcitriol (step 3). Calcitriol enhances calcium absorption in the brush borders of the intestine (step 6c), increasing serum calcium levels.

PTH acts on the kidney (step 4) to reduce calcium loss in urine by increasing its reabsorption, leading to increased serum calcium levels (step 6b).

Bibliography

Hall JE, Hall ME. Guyton and Hall Textbook of Medical Physiology. 14th ed. Elsevier – Health Science; 2020.

Shaker JL, Deftos L. PubMed. Published 2000. Web.

More related papers Related Essay Examples
Cite This paper
You're welcome to use this sample in your assignment. Be sure to cite it correctly

Reference

IvyPanda. (2023, September 1). Calcium and Phosphorus Metabolism. https://ivypanda.com/essays/calcium-and-phosphorus-metabolism/

Work Cited

"Calcium and Phosphorus Metabolism." IvyPanda, 1 Sept. 2023, ivypanda.com/essays/calcium-and-phosphorus-metabolism/.

References

IvyPanda. (2023) 'Calcium and Phosphorus Metabolism'. 1 September.

References

IvyPanda. 2023. "Calcium and Phosphorus Metabolism." September 1, 2023. https://ivypanda.com/essays/calcium-and-phosphorus-metabolism/.

1. IvyPanda. "Calcium and Phosphorus Metabolism." September 1, 2023. https://ivypanda.com/essays/calcium-and-phosphorus-metabolism/.


Bibliography


IvyPanda. "Calcium and Phosphorus Metabolism." September 1, 2023. https://ivypanda.com/essays/calcium-and-phosphorus-metabolism/.

If, for any reason, you believe that this content should not be published on our website, please request its removal.
Updated:
This academic paper example has been carefully picked, checked and refined by our editorial team.
No AI was involved: only quilified experts contributed.
You are free to use it for the following purposes:
  • To find inspiration for your paper and overcome writer’s block
  • As a source of information (ensure proper referencing)
  • As a template for you assignment
Privacy Settings

IvyPanda uses cookies and similar technologies to enhance your experience, enabling functionalities such as:

  • Basic site functions
  • Ensuring secure, safe transactions
  • Secure account login
  • Remembering account, browser, and regional preferences
  • Remembering privacy and security settings
  • Analyzing site traffic and usage
  • Personalized search, content, and recommendations
  • Displaying relevant, targeted ads on and off IvyPanda

Please refer to IvyPanda's Cookies Policy and Privacy Policy for detailed information.

Required Cookies & Technologies
Always active

Certain technologies we use are essential for critical functions such as security and site integrity, account authentication, security and privacy preferences, internal site usage and maintenance data, and ensuring the site operates correctly for browsing and transactions.

Site Customization

Cookies and similar technologies are used to enhance your experience by:

  • Remembering general and regional preferences
  • Personalizing content, search, recommendations, and offers

Some functions, such as personalized recommendations, account preferences, or localization, may not work correctly without these technologies. For more details, please refer to IvyPanda's Cookies Policy.

Personalized Advertising

To enable personalized advertising (such as interest-based ads), we may share your data with our marketing and advertising partners using cookies and other technologies. These partners may have their own information collected about you. Turning off the personalized advertising setting won't stop you from seeing IvyPanda ads, but it may make the ads you see less relevant or more repetitive.

Personalized advertising may be considered a "sale" or "sharing" of the information under California and other state privacy laws, and you may have the right to opt out. Turning off personalized advertising allows you to exercise your right to opt out. Learn more in IvyPanda's Cookies Policy and Privacy Policy.

1 / 1