Cell engineering techniques based on the use of fine organic synthesis are gaining popularity in modern medicine. Furthermore, as chemical synthesis advances, the profound molecular studies regarding the structure of both receptors and envelopes become less challenging. Another critical point is that these envelopes enable the cross of the species barrier for pathogenic viruses, and therefore, it is vital to research them along with receptors.
In addition, the focus of this academic work is the theoretical study of antiviral agents that can be used for the therapy of infections. It is significant to note that reliable vaccines for these diseases have not been created yet and require thorough research to enable their development. It is recognized that the most relevant areas of medicinal chemistry are those that pose the greatest threat to society.
For instance, nowadays, the most pressing issue is the global pandemic caused by the spread of Covid-19. This virus is spreading across the globe at a growing speed and infects considerable amounts of people (Pillaiyar et al., 2021). Moreover, Covid-19 can be easily transmitted from a human to a human (Pillaiyar et al., 2021). Thus, it is evident that the development of antivirus therapies is strongly and urgently required in order to decrease the rates of infected people and deaths due to the virus worldwide.
As a result, medicinal chemistry is concentrated on solving this severe problem by creating reliable vaccines that ensure high rates of survival and a complete lack of adverse side effects. Thus, the present study is based on a specific analysis of the coronavirus pathogen named SARS-CoV-2. To be more precise, the central part of this paper is mainly focused on the advancement of antiviral agents against the mentioned coronavirus pathogen, SARS-CoV-2. The critical point is the need for the detailed research of biochemical cases that are crucial for viral replication and pathogens lifespan within the cells. Furthermore, the biochemical mechanisms that hold virus entry into the target cell were studied and described in detail.
This research paper discusses the theoretical basis for common infection pathways and how they can be averted. Thus, the relevant data regarding SARS-CoV-2 is implemented as a source of predicting the chemical composition of antiviral agents beforehand. It is evident that at first, humanity needs to develop a functioning tool that can considerably reduce the rates of infected people and deaths due to the Covid-19 (Pillaiyar et al., 2021). Consequently, it would enable the creation and further development of a universal vaccine against the coronavirus by scientists. Overall, the paper concluded that among a large number of low molecular weight compounds, a set of 22 drugs with aromatic configuration had potential effectiveness (Pillaiyar et al., 2021). Therefore, the medical effects of these drugs were thoroughly investigated, which enabled the conclusion of the possible creation of the universal vaccine. In other words, the possible ways of inhibiting or destroying the active pathogen were described in detail.
In addition, the extensiveness of the study is ensured by a retrospective consideration of all known receptors that viruses can use to penetrate. Ultimately, it is recognized that either viral enzyme inhibitors or coreceptor bindings were of the most significant scientific interest because of their potential efficacy. Overall, the further study stages include the investigation of the active effects of such drugs. Consequently, the prospect of this study is determined by additional empirical findings and studies.
Works Cited
Pillaiyar, T., Wendt, L. L., Manickam, M., & Easwaran, M. “The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.” Medicinal research reviews 41.1 (2021): 72-135. doi:10.1002/med.21724