Introduction
The given data shows many people are obese and have hypertriglyceridemia because the index masse corporelle (ICM) surpasses the normal range of 30 while the triglycerides (TAG) levels are more than 150. This study explores if obesity could be a causing factor for increased triglycerides.
Research Questions for the Study
The questions that probe one to undertake this study will be more of a hypothesis than objectives or normal research questions. The reason is that from the data set given, an audience can observe that a given age has a trend in ICM and TAG levels. The same applies to obesity and hypertriglyceridemia since the two controlled variables can give a researcher a tip.
The following is the list of hypotheses:
- A high number of BMI affects the probability of having hypertriglyceridemia.
- The rate of triglycerides levels increases with the increase in obesity levels.
- Lipid irregularity is the pathogenies that cause obesity and hypertriglyceridemia.
Statistical Hypotheses
Null Hypothesis
People who are obese tend to have high triglycerides, which contributes to hypertriglyceridemia.
Alternative Hypothesis
Persons with obesity do not have a chance of getting hypertriglyceridemia.
Alpha Significance Level
The alpha significance level for this study is 5% since the alternative hypothesis may seem satisfying when the null hypothesis is true (Moore et al., 2017).
How the Study Will Contribute to Knowledge
The study will contribute to notable insights on how BMI levels relate to the chances of getting hypertriglyceridemia (Moore et al., 2017). Through the study, the audience will understand the key variables that necessitate a condition of increased triglycerides.
Literature Justification
When a person increases cholesterol levels, hormonal changes occur, one becomes exposed to increased triglycerides. There is observed lower muscle mass that makes one have a decreased metabolism rate. The relationship between triglycerides and BMI affects the chances of becoming obese due to the frequency of hypertriglyceridemia in patients with high BMI (Barbour et al., 2018). Obesity is considered a sensitive health issue in the US because it has led to the loss of life and poor living standards.
The major elements of the topic are the obesity and hypertriglyceridemia rates in society. Additionally, the age and sex perspectives are important while integrating the study hypotheses (Moore et al., 2017). Most of the literary sources’ arguments can be observed in the data from the files attached. For instance, a person with 35 BMI units has 234 units of triglycerides, meaning that the chances of getting hypertriglyceridemia increase with the obesity levels.
Theoretical Framework Guiding the Research Hypothesis
Patients who are obese have elevated serum triglyceride, which is caused by lipid abnormalities. The process leads to hepatic production of very-low-density lipoprotein (VLDL) elements that lead to hypertriglyceridemia (Wu et al., 2019). Lay theory suggests that the pathogenesis of obesity is due to unregulated calorie utilization in the body that is hindered by physical activity and complex interactions with healthcare systems. Lay theory also establishes the relationship between BMI and TAG levels, which are key in establishing whether obesity could be a causing factor for increased triglycerides. According to the lay theory of obesity, 96% of all dietary fats are triglycerides circulating in the bloodstream (Barbour et al., 2018). It is important to mention that obesity, caused by high cholesterol levels, makes the body have a metabolic process that makes particular hormones and the development of cells. Cholesterol is needed when triglycerides are used to fuel the body’s processes. Therefore, when one has high cholesterol levels, they have similar levels of having high triglycerides, which causes hypertriglyceridemia (Barbour et al., 2018). Thus, when one is obese, they have a chance of getting hypertriglyceridemia.
Hypertriglyceridemia is common in obese people, mostly the ones who are past the adolescent stage. According to a study done by Jung and Yoo (2018), there is an increasing prevalence of obesity in children and adolescents, which has become a sensitive issue. The study integrates the lay theory of obesity in that hypertriglyceridemia is common in obese children, and elevated triglyceride is observed where there is increased BMI (Jung & Yoo, 2018). Therefore, the known biomarker of cardiovascular risk comprises the elements that may lead to hypertriglyceridemia. When checking the data given, a person who has a BMI of 26 has 135 counts in terms of triglycerides counts. Therefore, the rate of getting hypertriglyceridemia is directly proportional to having a high BMI and vice versa. However, the trend may not be consistent due to age and genetic factors. For example, a person with 29 counts of BMI has 325 units of triglycerides, showing the discrepancy. However, the majority of the people in the data set show that when one is obese, they have a high number of triglycerides which leads to hypertriglyceridemia.
It is important to say that patients with obesity have been found to have frequent exhibitions of hypertriglyceridemia. The framework of hypertriglyceridemia in obesity perspectives has been associated with insulin resistance, a key factor in body mass index and triglycerides levels. An increased content of adipose tissue generated from free fatty acids (FFAs) enables high rates of hepatic triglyceride formation and development of VLDL elements (Vazquez‐Moreno et al., 2020). Evidence-based approaches to hyperinsulinemia suggest that insulin resistance is associated with the biosynthesis of triglycerides that comes from regulating cholesterol in the body. That shows the correlation between obesity and triglyceride levels in the probability of having hypertriglyceridemia. Hypertriglyceridemia is higher when people have high cholesterol levels that cause obesity, becoming the key cause of increased triglycerides. There is need to regulate the issue so that mortality rates are reduced in the society.
References
Barbour, L., Farabi, S., Friedman, J., Hirsch, N., Reece, M., Van Pelt, R., & Hernandez, T. (2018). Postprandial triglycerides predict newborn fat more strongly than glucose in women with obesity in early pregnancy. Obesity, 26(8), 1347-1356.
Jung, M., & Yoo, E. (2018). Hypertriglyceridemia in obese children and adolescents. Journal Of Obesity & Metabolic Syndrome, 27(3), 143-149.
Moore, D., Notz, W., & Fligner, M. (2017). The basic practice of statistics (8th ed.). W.H. Freeman and Company.
Vazquez‐Moreno, M., Perez‐Herrera, A., Locia‐Morales, D., Dizzel, S., Meyre, D., Stearns, J., & Cruz, M. (2020). Association of gut microbiome with fasting triglycerides, fasting insulin and obesity status in Mexican children. Pediatric Obesity, 16(5).
Wu, S., Darbinian, J., Ramalingam, N., Greenspan, L., & Lo, J. (2019). OR20-3 The relationship of obesity severity, triglycerides, and elevated ALT levels in adolescents. Journal of the Endocrine Society, 3(2), 24.