Main issues to be addressed
The first issue to be explored is the Quadrivalent Human Papillomavirus vaccine referred to as Gardasil. The text will include the indication and types of the vaccine, when and where it was first used. The dosage and administration of the vaccine into the human body are issues of exceptional importance in the topic. This will entail point and time of administration. The issue will include dosage, the reasons for Gardasil vaccine and the diseases it prevents. The topic will include who is to use the vaccine and the administration of the vaccine in exceptional cases like the young girls and expectant mothers. The ingredients of the vaccine will also be covered under this topic. Discussion will also consider the side effects of the Gardasil vaccine on the human body especially children. The issue will cover the precautions to be taken incase of any serious side effect and the presentation of the vaccine. The text will cover the cost of the vaccine Steve C. et al, (2007).
Human Papillomavirus (HPV) is the second issue to be discussed. The discussion will encompass the epidemiology of the HPV. The discussion will elaborate on the predisposing factors especially in young girls. These entail what makes a person more vulnerable to human papillomavirus virus than others. An overview of the HPV spread and progression into cervical cancer will be documented. The argument is going to cover the grave types of the virus like the cervical cancer, genital warts and other diseases associated with the human papillomavirus. The topic will provide an insight on the role of the body immune system in the development of HPV. The study will entail the development of the cervical cancer and treatment. Signs and symptoms of the diseases associated with the virus will also be covered. An overview of whom is at risk, where and when to seek treatment is also included. The topic will present the types of human papillomavirus that respond to the Gardasil vaccine and how vaccine works. The paper will describe the prevention of the Human Papillomavirus and other coping strategies for the infected especially the adolescents. The study will be focusing on the young females Ann M. et al (2009).
The relationship among Gardasil vaccine, human papillomavirus and the adolescents will be the third issue to be discussed. The topic will go deep into the problem and determine whether the Gardasil vaccine protects young girls against the virus HPV. The discussion will determine whether both males and females should get Gardasil vaccine and why. Other issue to be included is to which extent the vaccine has reduced the prevalence of the human Papillomavirus in the adolescents. The risk of both males and females to the diseases associated with the virus are of considerable importance in the text. The risks associated with the vaccination among girls and whether the vaccine gives long-term protection to this group. The regulations on compulsory vaccinations among adolescent females and where to get the vaccine are to be discussed in this text. The discussion will include the physiology and structure of the girls’ reproduction system that makes them more vulnerable than boys. Gail J. et al (2008).
Legislation and mandating of the Gardasil vaccine is the fourth field to be covered. Over forty one states have included the vaccination of female minor in their health strategies. Details in on legislation include issues such as mandatory vaccination for girls before school admission. Compelling the insurers to cover HPV vaccination in their packages and public health education on Gardasil vaccine are issues of importance. Legislation is the establishment of committees to put across recommendations on the vaccine. Another area to be covered in this sub-topic is the possible consequences of mandatory vaccination among the minors. The minimum age of vaccination and which gender to get the vaccine are to be discussed. The cost and insurance cover concerning the vaccine will also be elaborated Rebecca et al (2004).
Summary of what to be covered and details of the areas not to be covered
The task will include full information on the Gardasil vaccine. The presentation, administration, efficacy and side effects, are to be discussed. The human Papillomavirus and the associated diseases will also be discussed. Other areas to be visited on the vaccine are the cost, availability and the insurance cover for the adolescents. The text elaborates diseases like cancer of the cervix, genital warts and other diseases caused by the human papillomavirus. The discussion entails the advancement of the HPV into cancerous diseases. The issues revolving around the Gardasil vaccine and the young girls will also be covered in details. Other issues that must be entrenched include the state legislative activities on the human papillomavirus vaccine in relation to the adolescents. About 41 districts have stipulated strict legislations to address the Gardasil. Vaccination of young girls before admission to a school is required for admission. Another object to be included in the premature mandating of the vaccine and the inclusion of males in the vaccine.
The issue will not focus much on adults. Adult issues in relation to the Gardasil vaccine and human papillomavirus are to be left out of topic. A portion of it may be available in the discussion but, the assignment will revolve around children and adolescents. This is because the task revolves around the pediatrics and adolescents. The discussion will be revolving around young girls, and how the vaccine has contributed to the reduction of HPV prevalence among them. The issue will not stress on the human papillomavirus among the men. What to be covered is whether boys should get Gardasil vaccine. The Gardasil vaccine and the human Papillomavirus among the adults will not be applicable in the objectives of the topic.
Biotechnology of the vaccine specially the laboratory processes will not be captured in the topic area. The study will not portray the laboratory procedures and the structures of the proteins in the manufacturing of the vaccine. Discussion will miss out on the life cycle of the human papillomavirus. The topic will touch on the progression, but the detailed information will miss out. The issues pertaining to the genome of the human Papillomavirus cannot be covered in the text. Literature surrounding the HPV infection course is not going to be covered. The points will make the task so broad that it will lose the main objective. The biotechnology of the vaccine will include the utilization of laboratory procedures, which require long periods, to get the result. The reagents used in the laboratory are extraordinarily expensive which are not cost effective for the solution of the topic questions.
The third issue that will not be covered in the topic is the economic impact of the Gardasil vaccine. The lives saved by using the vaccine to prevent human papillomavirus and the cost of the reduction of incidence cases of the associated diseases. It will be devilishly difficult to provide detailed information on the economics about the vaccine. The cost benefit analysis of the vaccine has not been documented in many countries. There is little documentation about the economic impacts of the Gardasil and the human papillomavirus. The process incurs a lot of time and other resources to gather enough information to provide evidence based conclusion. The information available may be elaborating further on adults than the adolescents who are the main focus. The question is not concerned with the monetary gains of the Gardasil vaccine at this point. The economy is of importance, but the text will only touch on the areas of current concern.
The politics and problems especially critics of the vaccine will not be discussed in the topic areas. The critics and politics revolving around the vaccine efficacy, target population and cost of the vaccine are to be left out of the discussion. Other areas revolving around the question are vaccination versus abstinence and the implementation of the vaccine in the developing countries. The report will make them out because few researches are going on about the issues. The literature reviews on the stated issues are inadequate, and they do not provide sufficient information about the vaccine. The process of getting enough information will require many resources, which at the end, may not evolve into evidence based conclusion. The research is not concerned with the politics on the vaccine. It is not one of the set questions to be answered.
The discussion is to provide details of the four types of human papillomavirus in depth. The other remaining types will not be captured in details. The four types (18, 16, 11, & 6) are responsible for over 70% of cancer of the cervix and genital warts. The other types do not cause many illnesses. They are unusually many that they can not be discussed at full length. Some are not harmful to human health and will automatically disappear after some time. Some are also virulent enough to cause illnesses, but they are remarkably rare. To be left out are the issues on the screening techniques and procedures. The diagnostic processes of the genital wart and cervical cancer are to be excluded. The areas are crucial, but they do not directly answer the key questions entailed in the topic.
Another area, which will not be discussed, is the ethical considerations in the Gardasil and human papillomavirus research. The issues such as the informed consent will not be captured. The text will not capture the collection of data, so such issues will be of no importance on this topic. The issues such as beneficence, access to information and other moral issue during the testing of the Gardasil vaccine will not be included. The matter is only interested in the already published information specifically journals. The debate will not consider issues revolving around the data collection, presentation and analysis. The number of the subjects recruited in the study, and the inclusion criteria during the trials of the vaccine are not to be left out. The question is only interested in the results and how the vaccine functions.
Diagnosis of the genital warts, cancer of the cervix and other diseases associated with human papillomavirus will not be issues of importance in the topic area. These include the types of tests, the reagents used during diagnosis and other confirmatory tests. The topic is to be succinct and straight to its themes. The topic will lose its focus when diagnosis is entrenched in it. The clinical aspect to be included is only the administration of the vaccine and route of administration. The diagnosis issues are not relevant in the topic. Treatment of genital warts, cervical cancer and other associated diseases will not be covered in the topic. This includes the recommended drugs for human papillomavirus and management of the conditions associated with it. The matter is based in the prevention of the human papillomavirus among the adolescent girls and boys using Gardasil vaccine. Can gardasil vaccine prevent human papillomavirus? The documented data are to be used to give necessary information to the topic.
Points of view, what to answer and the importance of the topic
The topic is truly imperative because of my profession. The knowledge gained in the hospital gives some insight on the topic. I have general knowledge on the human papillomavirus and the Gardasil vaccine. Some adolescent girls are not aware of the virus and the now available vaccine which is a preventive measure. Some parents of the young girls are not aware of the issues surrounding the human papillomavirus and the new vaccine. It is one point that medical practitioners need to have lots of information.
There have been questions revolving around the issue of the Gardasil vaccine and the prevention of human papillomavirus. The field is still new and has a lot of research areas to be explored. My area of work puts me in a situation where I come into contact with female adolescents suffering from genital warts and other associated illnesses. Many patients come with varied conditions, which are associated, with the Human Papillomavirus. The wealth of the knowledge gained in the wards and some loopholes experienced is a driving force towards the topic. I have always known the human Papillomavirus both theoretically and practically, but more literature review has to be done.
The topic answers a series of questions about the Gardasil vaccine and human papillomavirus among the adolescents. The vaccine comes along with many issues. Human Papillomavirus is an issue of concern. The topic aims to answer the types of the vaccine, the administration, dosage, side effects and the precautions against the Gardasil vaccine. The questions on the contraindication, presentation, and the cost of the Gardasil vaccine Questions about who should get the vaccine will be answered by the topic. The topic will go ahead to answer the diseases caused by HPV, signs and symptoms. The epidemiology of the human papillomavirus is to be answered by the topic including the prevalence rates and the risk factors. The topic will cover the issues like prevention of human papillomavirus and management of the disease. The topic will answer the transmission and who is at risk of the human papillomavirus among the adolescents.
The topic covers many questions about the adolescents and the human Papillomavirus. The topic will find an insight in the prevalence of the human papillomavirus among the adolescent females and males. The topic aims to answer which sex to receive the Gardasil vaccine and why not the other. Another concern to be answered is whether the vaccine has caused a reduction in the incidence and prevalence in human papillomavirus among adolescents and by what margin. Has the vaccine caused a reduction in the risk of contracting human papillomavirus among the adolescent females? Questions about the legislation of the Gardasil vaccine are also expected to be answered.
The topic in question is decidedly paramount. The insight to be gained will be helpful in the proper management of patients with cases associated with human papillomavirus. Based on my profession, the results found about the vaccine and the HPV will improve my competency in the medical field. The improved competency will be a plus to the health of the general public. The truth to be unearthed will be disseminated to other professional around to improve their knowledge in their medical field. The adolescents have limited to resources. The information will help them in the prevention of the diseases associated with this dangerous virus. Adolescent girls will be in a position to get relevant information about human papillomavirus and how to take care of themselves.
Annotation of three sources
Ann M. et al (2009). Human Papillomavirus, Current Vaccines, and Cervical Cancer Prevention, JOGNN Journal, 69-77.
The article explores the question and answers about human Papillomavirus. It gives a broad insight into the general issues surrounding the virus and the vaccine. The article explains the fundamentals of the virus and its effects on human beings. The article covers various types of the virus like the lethal and no lethal strains of HPV. The transmission and prevention strategies are also covered. The transmission entails the entry mechanism and how it eventually turns into cervical cancer and other diseases. The diseases caused by the virus like the cervical cancer and genital warts are contained in the journal. Signs and symptoms of complicated diseases caused by the virus are also covered. The article explains who is at risk and other risk factors. It contains the HPV vaccine, the Gardasil. This article explains the administration of the vaccine, efficacy and the side effects. The role of the body immune system in the advancement of HPV is also contained in the text. The article explores the professional mandate and recommendations concerning the human papillomavirus vaccine.
The source is an immensely critical regarding the issue. The article illustrates a secure connection on the understanding of the human papillomavirus and the Gardasil vaccine. It gives a wide scope of the areas to be covered in the topic. This will provide an insight to the medical practitioners on how to connect the virus and the vaccine usage. The source touches on the adolescents and the human papillomavirus. It answers most of the questions the topic is aiming at. The key areas like the transmission and symptoms of the virus are well documented. The article elaborates the types of HPV. The recommendations for the medics like me are contained which will give an insight to deep understanding of the topic. The source contains both the HPV and the Gardasil vaccine. The article is, therefore, recommended to be a source on the topic due to its substantial coverage of the topics.
Carrie P. (2009). Questions Remain About Human Papillomavirus Vaccine. Cancer Scope journal, 699-701.
The Carrie’s article explores the efficacy and safety of the Gardasil vaccine. The reference material explores young girls and the consequences of the vaccine. The new vaccine in the market leaves many with questions unanswered. Parents and some individuals have raised questions on the negative side effects on their daughters. Other safety concerns addressed are deaths and Guil-lain-Barre syndrome. The prevention and management of the side effects are mentioned in the article. Other areas addressed in the text are the protection period and how it prevents other strains of HPV other than the four strains. The journal details out the statistics on the effectiveness of the vaccine. The article explores how the vaccination affects the natural resistance of adolescents and women. The impact on other oncogenic types of HPV is also captured in the article. The article details the recommended ages of administration among adult and adolescent females. The article gives summary statistics on the cost of vaccination for adults and how the female children can get free vaccination. The journal article proposes future research areas like the improvement of the efficacy time to extend beyond five years.
The article is exceedingly essential in finding solutions to the questions stated in the topic. It answers extremely challenging issues in the topic area. Side effects and effectiveness are matters of importance concerning the clients met in the health facilities. The article elaborates explicitly on the concerns of people regarding the vaccine. Knowledge gained from the authority gives enough confidence for the medical practitioners in handling patient fears regarding the vaccine. The article is, therefore, a highly relevant reference to the project work and can suggest other topics for future research.
Mark H. et al. (2006). The Epidemiology of Cervical Carcinogenesis. Journal of cancer, I-10.
Mark’s report elaborates widely on the epidemiology of the human papillomavirus and the proposed future researches. The article explores on how the cervical cancer, genital warts and other diseases occur. The infection of adolescent girls and young women with the varied types of HPV is also entailed in the text. What predisposes adolescents to the risk of human papillomavirus? The article illustrates lesions associated with the human papillomavirus in sexually active females. The journal article goes ahead to establish the causal association between human papillomavirus and the cervical cancer. This entails the pathogenesis of cancer of the cervix and its progression to extreme conditions.
Risk factors for genital warts and cervical cancer are reconsidered in the article. The sociodemographic factors are entirely elaborated here. The article entails the sexual and marital factors and how they predispose a person to the risk of contracting the disease. The issues in obstetric events are contained in the text. Linking the causation of the cervical cancer with other causal agents other than human papillomavirus is entrenched in the article. Attentions on the Chlamydia and herpes simplex virus are linked with the occurrence of the cervical cancer. The article gives an insight on the correlation involving the development of the cervical cancer and other cancers related to smoking. The article explains other pertinent risk factors like genetics, Immunosuppression, contraception, and cell type. Finally, the document proposes future areas of research like the research on human papillomavirus cofactors.
The document is crucial in the topic area. All the concerns on the transmission, statistics, and risk factors of the human papillomavirus will be understood. The correlation of cancer of the cervix with other viruses is a vital concern in the topic. A proper understanding of the human papillomavirus gives an insight in relating it with the Gardasil vaccine. The book is valuable because it states why females are at risk than men. Concern to the clients met in the health facilities. The article elaborates explicitly on the concerns. Knowledge gained from the source gives enough confidence of medical practitioners in handling patient fears regarding the vaccine. The article is, therefore, a highly relevant source in the project work.
Conclusion
The invention of the Gardasil to curb the incidence and prevalence of human papillomavirus among the girls is a significant progress in public health. Relevant sources back up the vaccine about its dosage, administration, and effectiveness. The vaccine gives hope towards the elimination of human papillomavirus. The annotated bibliographies are the best sources to elaborate more on Gardasil vaccine and the human papillomavirus. They give detailed reports in the subject areas thus answering the proposed questions. The insight gained is significant in improving the lives of minors and to the general public. The answered questions will indeed improve the quality of the health care services.
References
Gail J. et al (2008). Assessing Mandatory HPV Vaccination: Who Should Call the shots? Journal of law, medicine & ethics, 384-393.
Rebecca et al, (2004). HPV Communication: Review of Existing Research and Recommendations for Patient Education. A cancer journal for clinicians, 248-257.
Steve C. et al, (2007). Gardasil: first vaccine for human papillomavirus infection. Prescriber Journal, 1-4.