Introduction
An explicit review of this analytical paper resonates within an unlimited time frame. Reflectively, the review will authenticate the relevance of the research article which comprehensively captures conceptualization ideas discussed within its periphery of ideal and actualization. Besides, the review paper reflects on the methodology strategy and adopted methods that appear to have employed qualitative and quantitative analysis. In addition, the review investigates research designs and conceptualized results that are quantifiable and assess the same on oropharyngeal cancer. The scope in this scenario is to capture the existing association between oropharyngeal cancers and HPV. In the conclusive segment, evaluation of originality and conceptualization are placed in order to ensure relevance in the review of prospect schema.
Methodology Analysis and Discussion
The article captured data on 130 patients freshly diagnosed with oropharyngeal cancer to collect oral-mucosal specimens for HPV detection. As observed in the research methodology, the author employed the use of quantitative research methodology which measures assumptions given and reflectively develops quantifiable results that were obtained via interviews on medical history, hygiene, among other relevant variables. In order to obtain actual and study physical reactions for different specimens, the researchers adopted a nonbiased tool for obtaining data. Therefore, the research article is very specific on both qualitative and quantitative data collection and analysis approaches that were simultaneously employed in the research. Through examination of the HPV-16 in the sample specimens, the researchers were in a position to further carry out DNA analysis for 37 HPV types. In order to stay within the scope of the research, viral load reporting was necessary for positive samples with adjustments made where necessary.
Subject Results
The author employs simple correlation analysis involving the measurement of dependent and independent variables. The simultaneous application and measurement of independent and dependent variables are great and capture the true value representation of the target population. Through use intrusive regression analysis that quantifies the relationship between the two variables (positive and negative results). The article was in a position to explain the relationship between the two variables that can be expanded to more variables grouped in pairs. Reflectively, the authors found out that when an enzyme-linked immunosorbent assay (ELISA) of virus resembling particles were used, antibodies of Serum nature were detected for HPV-16 L1. On the other hand, the use of ELISA and bacteria-like particles indicated detection of antibodies parallel to HPV-16 E6 and HPV-16 E7 oncoproteins and these indicated full length as in the antigen.
Discussion
The article has succeeded in supporting the intrinsic association between the oropharyngeal cancers subgroup and HPV. Despite the fact that the cause-effect tie is not possible to quantify from one study, the authors were in a position to present the extent f variances between the control and actual studies. In this case, it is important to note that prolonged exposure to HPV is likely to precede oropharyngeal cancer appearance for several years. However, secondary factors such as tobacco and alcohol may induce genomic instability. In addition, the study concluded that sexual behaviors may increase the risk of ‘squamous-cell carcinomas’. Due to t these secondary factors, the authors concluded that the history of the family on squamous-cell carcinomas’, substance abuse, and poor oral personal hygiene are depository factors to oropharyngeal cancers.
Conclusion
The most essential part of a properly written research paper should reflect on conceptualization and maintain originality. This research paper provides a clear link between one variable to another and is majorly based on factual information. Besides, the analysis presents a complete reflection of the actual situation on oropharyngeal cancers.